Mr Capstick, a dealer in old photographs, acquired the photograph and noticed it was printed in Commercial Road, Hereford, even though it may not have been taken in the city.
Althea McKenzie, the museum's costume and textile curator, suggests the uniforms and clothing date the scene to around 1900-1910.
David Stevens, Hereford Museum's collections officer for social history, said: "We would like to know whether anyone can shed any light on this true leather working curio and whether it was a Hereford team or a major event that needed such a giant football to be made.
"We have drawn a blank in the museum, apart from being able to give some idea of the date of the photograph, and would be grateful for any information," he added.
Anyone who can help should contact David Stevens on 01432 383387.